Description:

This course will present an integrated introduction to general mechanisms of cell, tissue and organ injury (general pathology), the principal mechanisms of responses to injury and defense against foreign invaders (inflammation and immunity), and the major groups of microbial pathogens that cause human disease (microbiology and infectious diseases). Students will gain an understanding of: 1) general pathological mechanisms underlying disease of all organ systems, with an emphasis on cell injury and death, thrombosis, atherosclerosis, ischemia, and infarction, and neoplasia; 2) the anatomic and molecular manifestations of general pathologic processes; 3) the normal and abnormal functions of the innate and adaptive immune systems; and 4) the aspects of microbial structure, replication or growth, which are relevant to pathogenicity and treatment. The course will be taught using lectures, case-based, small group tutorial sessions, patient presentations, conferences and laboratories.

Evaluation:

Written exam and classroom and tutorial performance