NN503M.3

Advanced Study in Neuropathology

Sites: MGH
Director(s): Matthew Frosch, Alberto Puig
Prerequisites: HMS Principal Clinical Experience (Core Clinical Clerkships) or equivalent
Offered: Full time for one month.
Location: MGH - Mass. General Hospital (3)
Open to Exclerks: Yes (may be restricted for international students)
Description: The course consists of participation in ongoing examinations of surgical and autopsy neuropathology specimens, attendance at teaching conferences and case discussions and individual study of the pathologic-anatomical aspects of diseases of the human nervous system, based upon a large collection of illustrative material on file. The diagnostic neuropathology service of MGH includes a large volume of neoplasms (mostly primary brain tumors), nerve nad muscle diseases, neurologic diseases and neurodegenerative disorders. Students are expected to prepare a case with detailed clinicopathologic correlation. Particular exposure to neurodegenerative diseases and to molecular neurooncology may also be arranged.
Incorporation of Basic Science Content and Evidence-Based Medicine:
Underlying pathophysiology and basic science concepts relevant to neurologic diseases are discussed during daily signout sessions for both surgical and autopsy neuropathology cases. These concepts are reinforced and linked to Evidence-Based Medicine through several weekly conferences, including Molecular Pathology Research conference, Tumor Boards (2 per week), Neuromuscular Pathology conference, and Brain Cutting conferences (2 per week).
Grade Criteria:
Honors with Distinction: Enthusiastic participation in all activities of the neuropathology service. Knowledgeable and thoughtful preparation of assigned cases, including discussion of the underlying pathophysiology as well as the diagnostic neuropathologic features, including the ability to go beyond the prepared material when leading the discussion with the staff neuropathologists -- typically at the level expected of a pathology trainee. Honors: Consistent and active participation in all activities of the neuropathology service. Knowledgeable and thoughtful preparation of assigned cases, including discussion of the underlying pathophysiology as well as the diagnostic neuropathologic features -- typically at the level expected of a senior medical student. Satisfactory: Consistent but passive participation in all activities of the neuropathology service. Acceptable preparation of assigned cases, including at least partial discussion of the underlying pathophysiology as well as the diagnostic neuropathologic features Unsatisfactory: Incomplete participation in expected activities of the neuropathology service. Incomplete presentation of assigned case (lacking insight into disease mechanisms, lacking sophistication in interpretation of pathologic findings). OR Evidence of inadequate levels of professionalism for level of medical education