HT194.0

Clinical Epidemiology: Methods for Clinical Research

Credits: 0 CREDITS (Basic Science)
Director(s): 0 CREDITS (Basic Science)
Prerequisites: Intermediate biostatistics
Offered: 17-Jan
Location: HMS - Harvard Medical School (0)
Open to Exclerks: No (HMS only)
Description: Clinical research is used to describe, predict, and make causal inferences. This course introduces the methods for the generation, analysis, and interpretation of data for clinical research. Major topics include the design of surveys, predictive models, randomized trials, clinical cohorts, and analyses of electronic health records. Students will learn to formulate well-defined research questions, to design data collection, to evaluate algorithms for clinical prediction, to design studies for causal inference, and to identify and prevent biases in clinical research. Familiarity with regression modeling and basic statistical theory is a pre-requisite. The course emphasizes critical thinking and practical applications, including daily assignments based on articles published in major clinical journals and the discussion of a case study each week. A key goal of the course is training students to comprehend, critique, and communicate findings from the biomedical literature.
Grade Criteria:
Students will be evaluated on two criteria
• 5 homework assignments
• Take-­‐home exam